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Simple renal cysts in children with AIDS
H L Zinn1, S T Rosberger, J O Haller
1Department of Radiology, State University of New York, Health Science Center at Brooklyn, 450 Clarkson Avenue, Box 1208, Brooklyn, NY 11203, USA.
Pediatric Radiology
|November 5, 1997
Summary
Simple renal cysts are rare in children but were found in 4 of 50 pediatric AIDS patients. This suggests simple renal cysts may indicate HIV nephropathy (HIVN) in children.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Radiology
Background:
- Simple renal cysts are uncommon in the pediatric population.
- Acquired immunodeficiency syndrome (AIDS) can affect multiple organ systems, including the kidneys.
Observation:
- Computed tomography (CT) scans of 50 children with AIDS revealed 4 cases of simple renal cysts.
- This represents an incidence approximately 45 times higher than in the general pediatric population.
Findings:
- Simple renal cysts have not been previously reported as a manifestation of pediatric AIDS.
- The presence of simple renal cysts in children with AIDS may be associated with HIV nephropathy (HIVN).
Implications:
- Simple renal cysts could serve as a potential imaging biomarker for HIV nephropathy in children.
- Further research is warranted to confirm the association between simple renal cysts and HIVN in pediatric patients.