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Fetal and infant deaths associated with maternal methamphetamine abuse

J L Stewart1, J E Meeker

  • 1Institute of Forensic Sciences, Oakland, California 94609, USA.

Journal of Analytical Toxicology
|November 5, 1997
PubMed
Summary

Maternal methamphetamine abuse is linked to fetal and infant deaths. This study found significant methamphetamine concentrations in fetal blood, indicating a direct toxic effect.

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The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...