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Chronic relapsing brachial plexus neuropathy with persistent conduction block

A A Amato1, C E Jackson, J Y Kim

  • 1Department of Neurology/Medicine, University of Texas Health Science Center at San Antonio, 78284-7883, USA.

Muscle & Nerve
|October 27, 1997
PubMed
Summary
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Idiopathic brachial plexus neuropathy typically presents as sudden, painful weakness. This case report details a rare, chronic, relapsing form with painless weakness and demyelination, responding to IVIg treatment.

Area of Science:

  • Neurology
  • Immunology
  • Neurophysiology

Background:

  • Idiopathic brachial plexus neuropathy (BPN) is an immune-mediated disorder.
  • Typically presents with acute, painful weakness, usually monophasic.
  • Pathogenesis is often axonal, with gradual recovery.

Observation:

  • This report describes an atypical BPN case.
  • The patient experienced chronic, relapsing, painless weakness.
  • Electrophysiology revealed conduction blocks and demyelination.

Findings:

  • The neuropathy exhibited features of demyelination, not typically seen in BPN.
  • The chronic and relapsing course suggests overlap with other neuropathies.
  • Treatment with intravenous immunoglobulin (IVIg) led to improvement.

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Implications:

  • This case expands the spectrum of BPN presentation.
  • It highlights the potential overlap between BPN, CIDP, and MMN.
  • Suggests considering demyelinating neuropathies in relapsing brachial plexus disorders.