Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tracking the MEN1 gene

S A Ebrahimi1, M P Sawicki

  • 1Department of Surgery, West Los Angeles Veterans Affairs Medical Center, and the University of California, Los Angeles, School of Medicine, USA.

American Journal of Surgery
|October 27, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Maternal voluntary exercise ameliorates learning deficit in rat pups exposed, in utero, to valproic acid; role of BDNF and VEGF and their receptors.

Neuropeptides·2018
Same author

Biocompatible polymer microneedle for topical/dermal delivery of tranexamic acid.

Journal of controlled release : official journal of the Controlled Release Society·2017
Same author

Development of micellar electro kinetic chromatography for the separation and quantitation of L-valine, L-leucine, L-isoleucin and L-phenylalanine in human plasma and comparison with HPLC.

Pakistan journal of biological sciences : PJBS·2008
Same author

Effects of mebudipine and dibudipine, two new calcium channel blockers on voltage-activated calcium currents of PC12 cells.

Acta physiologica Hungarica·2007
Same author

Interaction of papaverine with the enalapril-induced cough in guinea pig.

Acta physiologica Hungarica·2006
Same author

Effects of mebudipine and dibudipine, two new calcium channel blockers, on guinea-pig isolated common bile duct.

Acta physiologica Hungarica·2004
Same journal

Innovative management of Anterior Cutaneous Nerve Entrapment Syndrome (ACNES): A meta-analysis and introduction of a new robotic approach with patient-based algorithm.

American journal of surgery·2026
Same journal

Does the risk outweigh the benefit? Clot progression, recanalization & complications of anticoagulation therapy in acute pancreatitis with concomitant splanchnic vein thrombosis.

American journal of surgery·2026
Same journal

High and low body mass index and 90-day postoperative outcomes in patients with Crohn's disease undergoing abdominal surgery.

American journal of surgery·2026
Same journal

Women with firearm injuries: A multicenter mixed-methods study.

American journal of surgery·2026
Same journal

SBAS presidential address: A surgeon-scientist's journey from haptic science to digital performance metrics.

American journal of surgery·2026
Same journal

Using Dr. Google and AI to stay informed.

American journal of surgery·2026
See all related articles

Multiple endocrine neoplasia type 1 (MEN1) is a genetic disorder. Researchers are using molecular genetics to find the tumor suppressor gene responsible for MEN1 in sporadic pancreatic tumors.

Area of Science:

  • Endocrinology
  • Genetics
  • Oncology

Background:

  • Multiple endocrine neoplasia type 1 (MEN1) is an inherited disorder.
  • MEN1 involves parathyroid hyperplasia, pancreatic endocrine tumors, and pituitary adenomas.
  • Sporadic tumors share genetic links with MEN1.

Purpose of the Study:

  • To identify the tumor suppressor gene responsible for MEN1.
  • To investigate the molecular genetics of sporadic pancreatic endocrine tumors.

Main Methods:

  • Positional cloning techniques.
  • Molecular genetic analysis of sporadic tumors.

Main Results:

  • The study focuses on the strategy for gene isolation.
  • Details of molecular genetic techniques are provided.

Related Experiment Videos

Conclusions:

  • Understanding the genetic basis of sporadic tumors is key to identifying MEN1-related genes.
  • Positional cloning is a viable strategy for tumor suppressor gene discovery.