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Updated: Oct 1, 2026

Human Pluripotent Stem Cell Based Developmental Toxicity Assays for Chemical Safety Screening and Systems Biology Data Generation
Published on: June 17, 2015
[Value of estimation of stress during human toxico-genetical investigations]
F I Ingel'1, A M Prikhozhan, T E Tsutsman
1HII of Profilactic Toxicology and Disinfection, Moscow.
Abstract:
The paper presents the monitoring results of the genetic and mental status of workers from 2 plants of Yaroslavl. The groups of the examinees were formed in terms of unhealthy working conditions and residence in clean or polluted areas of the city. The individuals working under harmful and living under unfavourable environmental conditions were found to be more commonly acute or chronically stressed or fatigable than the control workers. Those under stress were shown to be more responsive to environmental genetic toxic agents. Whether psychological training may be used to form groups at high genetic risk is discussed.

