[Diagnosis and therapy of fungal keratitis--a review]

The diagnosis and current therapy of keratomycosis is presented in an overview. The following characteristics are helpful in clinical diagnosis: unsharp borders of the infiltrate, elevated infiltrate with initially epithelium, satellites and pyramidal hypopyon. The microbiological and microscopic confirmation is often possible only after repeated debridements. Lactophenol Blue is very suitable for staining the material obtained. Fluconazol is recommended for the local treatment of candida keratomycosis. Alternatively, amphotericin B is a potent antimycotic. However, a debridement is necessary to enhance bioavailability of this drug. If pharmacotherapy is not efficient enough, keratoplasty should be performed as soon as possible.