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[Pancreatic polypeptide secreting endocrine pancreas tumor associated with multiple stomach and duodenal ulcers]
U M Mehring1, H J Jäger, G Klöppel
1Institut für Allgemeine Pathologie und Pathologische Anatomie, Christian-Albrechts-Universität Kiel.
Langenbecks Archiv Fur Chirurgie
|January 1, 1997
Abstract:
A 58-year-old woman presented with multiple gastroduodenal ulcera caused by a pancreatic polypeptidoma (PPoma) without hypergastrinemia or gastrin-producing tumor cells. After curative resection of the neoplasm, the clinical symptoms disappeared and the patient has now been disease-free for 6 years. We conclude that patients with non-gastrin-producing endocrine pancreatic tumors may demonstrate the clinical features of Zollinger-Ellison syndrome and should be included in the differential diagnosis of this syndrome.