Related Experiment Videos
[Immunologic bases of graft vs. host disease: 1997]
1Kisérletes Csontvelötranszplantációs Laboratórium, Országos Haematológiai és Immunológiai Intézet, Budapest.
Orvosi Hetilap
|August 31, 1997
Abstract:
The development of a graft-versus-host reaction after hematopoietic stem cell transplantation is an important determinant of the transplant outcome. The existence of subsets of CD4+ helper T-lymphocytes that differ in their cytokine secretion patterns and effector functions provides a framework for better understanding and improved management of the graft-versus-host reaction. It should allow improved prevention and treatment of graft-versus-host disease and the development of new strategies to enhance a graft-versus-leukemic relapse after transplantation.