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Related Experiment Videos

[Generalized weakness in pre-existing achalasia]

G Schulthess1

  • 1Abteilung für Innere Medizin, Spital Limmattal, Zürich.

Praxis
|July 2, 1997
PubMed
Summary

A 77-year-old woman with achalasia experienced infectious anemia and hypoproteinemia, potentially due to bacterial overgrowth from an esophageal diverticulum. Antibiotic treatment showed temporary success, highlighting a complex interplay between esophageal conditions and systemic health.

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Area of Science:

  • Gastroenterology
  • Internal Medicine
  • Infectious Diseases

Background:

  • The patient, a 77-year-old female, had a history of achalasia and an epiphrenic diverticulum, previously managed with endoscopic dilatations.
  • She presented with general weakness and a fall, leading to the discovery of a pelvic fracture, anemia, and hypoproteinemia.

Observation:

  • Upper gastrointestinal endoscopy revealed severe mucosal inflammation.
  • The patient exhibited microcytic hypochromic anemia and marked hypoproteinemia.

Findings:

  • A hypothesis was formed suggesting bacterial overgrowth from the esophageal diverticulum spread to the upper gastrointestinal tract.
  • This bacterial spread was postulated to cause infectious anemia and protein-losing enteropathy.

Implications:

  • Treatment with cotrimoxazole (antibiotic) led to improvement in anemia and hypoproteinemia.
  • These conditions relapsed upon discontinuation of the antibiotic therapy, indicating a persistent underlying issue.

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