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Brief note. Induction of experimental allergic encephalomyelitis in sheep with purified bovine basic protein and
Pathology
|July 1, 1979
Abstract:
A large animal model for the induction of experimental allergic encephalomyelitis to study the immunological disease parameters through closed-circuit extracorporeal thoracic duct filtration was successfully produced in two different strains of sheep. This study demonstrates the advantages of using a well-defined antigen to obtain both rapid onset of disease and a higher percentage of animals succumbing to the illness.