Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Late ventricular potentials and heavy drinking

G Pochmalicki1, M Genest, H Jibril

  • 1Service de Cardiologie, C.H.G. Léon Binet, Provins, France.

Heart (British Cardiac Society)
|August 1, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Psychological treatment of depression: cognitive behavioural therapy.

Canadian family physician Medecin de famille canadien·2011
Same author

[A familial form of conduction defects associated with a PRKAG2 gene mutation].

Archives des maladies du coeur et des vaisseaux·2007
Same author

[Management of sudden death in a semi-rural district, Seine-et-Marne: the DEFI 77 study].

Archives des maladies du coeur et des vaisseaux·2007
Same author

Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations.

European biophysics journal : EBJ·2007
Same author

[Cage failure following replacement of the third lumbar vertebral body in Hodgkin's disease].

Zeitschrift fur Orthopadie und ihre Grenzgebiete·2006
Same author

Lateral mobility of proteins in liquid membranes revisited.

Proceedings of the National Academy of Sciences of the United States of America·2006
Same journal

Feasibility of early double sequential defibrillation in out-of-hospital cardiac arrest: the double-D randomised pilot trial.

Heart (British Cardiac Society)·2026
Same journal

Correspondence on 'When a patent foramen ovale becomes pathological' by Saji and Ohara.

Heart (British Cardiac Society)·2026
Same journal

Cost-effectiveness of N-terminal pro-B-type natriuretic peptide thresholds for echocardiography referral in primary care heart failure management.

Heart (British Cardiac Society)·2026
Same journal

Optimal timing of aspirin discontinuation after acute coronary syndrome treated with percutaneous coronary intervention: a systematic review and meta-analysis.

Heart (British Cardiac Society)·2026
Same journal

Importance of rating: the impact of establishing age and sex normative values for left ventricular strain rate.

Heart (British Cardiac Society)·2026
Same journal

Man in his 40s with palpitations.

Heart (British Cardiac Society)·2026
See all related articles

Chronic alcohol consumption linked to heart abnormalities, specifically late ventricular potentials (LVP), correlating with liver damage. Signal-averaged ECG detects these changes in individuals with alcohol-induced fatty liver disease.

Area of Science:

  • Cardiology
  • Hepatology
  • Electrophysiology

Background:

  • Chronic alcohol abuse is a significant public health concern with known systemic effects.
  • Alcohol's impact on cardiac function, particularly subtle electrical changes, requires further investigation.
  • Liver disease, such as steatosis, is a common consequence of chronic alcohol consumption.

Purpose of the Study:

  • To evaluate the impact of chronic alcohol intake on the detection of low-amplitude signals in the electrocardiogram.
  • To investigate the relationship between late ventricular potentials (LVP) and histological findings from liver biopsies in chronic alcoholics.

Main Methods:

  • A prospective study was conducted involving 41 consecutive chronic alcoholics.
  • Standard ECG, echocardiography, signal-averaged electrocardiogram (SAECG), liver biopsy, and blood tests were performed approximately four days after the last alcoholic drink.

Related Experiment Videos

  • Data analysis focused on correlating SAECG parameters with liver biopsy results, specifically steatosis.

    • Main Results:

    • Late ventricular potentials (LVP) were detected in 28% of the study participants.
    • A significant correlation was observed between the degree of hepatic steatosis and specific SAECG parameters: the amplitude of the last 40 ms of the average QRS complex (P=0.04), the duration of the terminal low-amplitude QRS signal (P=0.05), and the number of positive criteria for late potentials (P=0.02).

    Conclusions:

    • Chronic alcohol consumption, particularly when severe enough to cause hepatic steatosis, is associated with abnormal findings on signal-averaged electrocardiograms.
    • These findings suggest that SAECG may serve as a non-invasive indicator of cardiac electrical alterations in chronic alcoholics with liver disease.