Related Experiment Video
Updated: Aug 9, 2026

12:06
Molecular Diffusion in Plasma Membranes of Primary Lymphocytes Measured by Fluorescence Correlation Spectroscopy
Published on: February 1, 2017
Flow cytometry applications in pharmacodynamics and drug delivery
1Department of Pharmaceutics, State University of New York at Buffalo 14260-1200, USA. murali@acsu.buffalo.edu
Pharmaceutical Research
|November 5, 1997
Abstract:
We highlight recent advances in flow cytometry that have potential applications in the pharmaceutical sciences, particularly in pharmacodynamics and drug delivery. These advances are discussed in the context of the preclinical development of anticancer agents, immunosuppressants and immunomodulators, and oligonucleotides and gene therapy.
Related Concept Videos
Flow Cytometry
The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...
In...
Measurement of Bioavailability: Pharmacodynamic Methods
Pharmacodynamic methods provide insights into a drug's effects on physiological processes over time and play a crucial role in understanding bioavailability and therapeutic efficacy. These methods can be broadly classified into acute pharmacological and therapeutic response approaches, each with distinct mechanisms and applications.The acute pharmacological response method directly correlates a drug's physiological effects, such as ECG or pupil diameter changes, to its time course in the body.

