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On localizing schizophrenic neuropathology

D R Weinberger¹

¹Clinical Brain Disorders Branch, IRP, NIMH, NIH Neuroscience Center at St. Elizabeths Hospital, Washington, DC 20032, USA.

Schizophrenia Bulletin

|January 1, 1997

Summary

Schizophrenia neuropathology involves temporal limbic and frontal-thalamic brain circuits. While evidence suggests their role, current data on brain structure changes in schizophrenia remains incomplete and inconsistent, requiring further research.

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Area of Science:

Neuroscience
Psychiatry

Background:

Schizophrenia is a complex brain disorder with neuropathology implicated in various brain regions.
Previous research has linked temporal limbic structures and frontal-thalamic circuits to the disease.