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Related Experiment Videos

Peripheral motor nerve function in diabetic autonomic neuropathy

D J Ewing, A A Burt, I R Williams

    Journal of Neurology, Neurosurgery, and Psychiatry
    |May 1, 1976
    PubMed
    Summary

    Diabetic autonomic neuropathy is linked to peripheral nerve changes. Autonomic nervous system dysfunction in diabetes correlates with nerve conduction abnormalities, suggesting a need for screening.

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    Area of Science:

    • Neurology
    • Diabetology
    • Autonomic Neuroscience

    Background:

    • Diabetic neuropathy is a common complication.
    • Autonomic neuropathy affects multiple organ systems.
    • Peripheral nerve involvement is well-documented in diabetes.

    Purpose of the Study:

    • To investigate the relationship between autonomic neuropathy and peripheral nerve function in diabetic patients.
    • To assess if autonomic dysfunction correlates with specific peripheral nerve conduction abnormalities.

    Main Methods:

    • Measured motor conduction velocity in median, ulnar, and common peroneal nerves.
    • Assessed autonomic nervous system integrity using Valsalva maneuver, sustained handgrip, and postural blood pressure changes.
    • Correlated autonomic function test results with peripheral nerve parameters.

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    Main Results:

    • Abnormalities in autonomic function tests were significantly correlated with ulnar and common peroneal nerve conduction velocities.
    • Common peroneal nerve motor latency and H reflex also showed significant correlations.
    • Autonomic nervous system abnormalities parallel peripheral nerve changes in diabetics.

    Conclusions:

    • Diabetic autonomic neuropathy is associated with peripheral nerve dysfunction.
    • Peripheral nerve conduction studies may reflect autonomic nervous system involvement in diabetes.
    • Diabetics with peripheral neuropathy require evaluation for autonomic nervous system complications.