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Published on: November 15, 2015
Nylon cloth macular amyloidosis
1Department of Dermatology, Queen's University Hospital, Nottingham, UK.
Abstract:
In primary localized cutaneous amyloid, deposition of amyloid is confined to the skin without the involvement of any internal organs. Amyloid deposition in the skin is often scanty, and electron microscopy may be needed to confirm the presence of the typical amyloid fibrils. There have been several case reports of cutaneous amyloidosis associated with friction or rubbing of the skin. We report a case of primary localized cutaneous amyloid associated with the habitual use of a nylon cloth.
Insights
Primary localized cutaneous amyloidosis, a skin-only condition, can be linked to skin friction. This case highlights a connection between habitual nylon cloth use and this rare form of amyloidosis.
Area of Science:
- Dermatology
- Pathology
- Medical Research
Background:
- Primary localized cutaneous amyloidosis involves amyloid deposition solely in the skin.
- Amyloid deposits in the skin are often minimal, requiring electron microscopy for confirmation.
- Previous reports suggest a link between cutaneous amyloidosis and skin friction or rubbing.

