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[The effect of Japanese herbal medicine on MRSA carrier in neurosurgery]
H Karibe1, T Kumabe, Y Ishibashi
1Department of Neurosurgery, Watanabe Hospital.
Abstract:
Since the management of methicillin-resistant staphylococcus aureus (MRSA) carriers is not established, these patients are isolated individually, limited in activity, and delayed in rehabilitation. In this study, the effect of Japanese herbal medicine on MRSA carriers was examined. In the control group, MRSA carriers were isolated individually. In the treatment group, one of the Japanese herbal medicines "Juzentaihotou" or "Hotyuekkitou" was given in addition to isolating the patient. It was shown in cultures that Japanese herbal medicines had effectively changed MRSA carriers to negative. They also shortened the duration required to bring about the change of MRSA carriers to negative. As a result, the total number of MRSA carriers was reduced. These results suggested that Japanese herbal medicines may be useful for the management of MRSA carriers in neurosurgery.
Insights
Japanese herbal medicines, Juzentaihotou and Hotyuekkitou, effectively convert methicillin-resistant Staphylococcus aureus (MRSA) carriers to negative. This approach reduces MRSA carrier duration and numbers, offering a potential management strategy in neurosurgery.
Area of Science:
- Infectious Diseases
- Pharmacology
- Neurosurgery
Background:
- Management of methicillin-resistant Staphylococcus aureus (MRSA) carriers lacks established protocols.
- Current MRSA carrier management involves isolation, activity restriction, and delayed rehabilitation.
- The need for effective strategies to manage MRSA colonization, particularly in clinical settings.
Purpose of the Study:
- To investigate the efficacy of Japanese herbal medicines in managing MRSA carriers.
- To evaluate the impact of Juzentaihotou and Hotyuekkitou on MRSA carrier status.
- To assess the potential of herbal medicine as an alternative or adjunct therapy for MRSA carriers in neurosurgery.
Main Methods:
- A study comparing a control group (standard isolation) with a treatment group receiving Japanese herbal medicine (Juzentaihotou or Hotyuekkitou) alongside isolation.
- Utilized microbiological cultures to determine MRSA carrier status.
- Monitored the duration for MRSA carriers to convert to negative status.
Main Results:
- Japanese herbal medicines demonstrated effectiveness in converting MRSA carriers to a negative status.
- Treatment groups showed a shortened duration for achieving MRSA negativity compared to the control.
- A reduction in the overall number of MRSA carriers was observed in the treatment groups.
Conclusions:
- Japanese herbal medicines, specifically Juzentaihotou and Hotyuekkitou, show promise in managing MRSA carriers.
- These herbal interventions can accelerate the clearance of MRSA, reducing carrier duration and prevalence.
- Herbal medicine may be a valuable therapeutic option for MRSA carrier management in neurosurgical patients.