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Primary central nervous system leukemia with a novel chromosomal translocation
T Hayashi1, J Onodera, H Mochizuki
1Department of Neurology, Tohoku University School of Medicine, Sendai, Japan.
Journal of the Neurological Sciences
|October 23, 1997
Summary
This study describes a rare case of central nervous system (CNS) leukemia presenting with normal bone marrow and a novel chromosomal abnormality (4q+, 10q-, 16q-). This finding offers insights into the mechanisms of primary leukemic meningitis.
Area of Science:
- Hematology
- Neurology
- Cytogenetics
Background:
- Central nervous system (CNS) leukemia typically involves bone marrow abnormalities.
- Leukemic meningitis without bone marrow involvement is exceptionally rare.