Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Estrogens and breast cancer

S E Hankinson1, M J Stampfer

  • 1Channing Laboratory, Brigham and Women's Hospital, Boston, MA, USA.

Salud Publica De Mexico
|July 1, 1997
PubMed
Summary

Oral contraceptive use shows little risk increase for breast cancer, though current use may slightly elevate risk temporarily. Long-term postmenopausal hormone use is linked to a notable increase in breast cancer risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

No association between a polymorphic variant of the IRS-1 gene and prostate cancer risk.

The Prostate·2008
Same author

Comparison of aspects of smoking among the four histological types of lung cancer.

Tobacco control·2008
Same author

HbA1c measured in stored erythrocytes and mortality rate among middle-aged and older women.

Diabetologia·2007
Same author

Circulating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohorts.

British journal of cancer·2007
Same author

Validation of a food frequency questionnaire measurement of selected nutrients using biological markers in African-American men.

European journal of clinical nutrition·2007
Same author

Cardiovascular disease and Alzheimer's disease: common links.

Journal of internal medicine·2006

Area of Science:

  • Reproductive Health
  • Oncology
  • Epidemiology

Background:

  • Oral contraceptives (OCs) and postmenopausal hormone therapy (PHT) are widely used.
  • Understanding their impact on breast cancer risk is crucial for informed decision-making.

Purpose of the Study:

  • To review epidemiologic evidence on OCs and PHT and breast cancer risk.
  • To explore the biologic plausibility of these associations.

Main Methods:

  • Systematic review of epidemiologic studies.
  • Analysis of biologic mechanisms potentially linking hormone use to breast cancer.

Main Results:

  • OC use generally shows minimal breast cancer risk increase, even with long-term use.
  • Current OC users may have a modest, temporary risk elevation that resolves post-cessation.
Keywords:
BiologyBreast CancerCancerContraceptionContraceptive MethodsDemographic FactorsDiseasesEndocrine SystemEstrogensFamily PlanningHormone Replacement TherapyHormonesLiterature ReviewNeoplasmsOral ContraceptivesPhysiologyPopulationPopulation DynamicsRisk FactorsTime FactorsTreatment

Related Experiment Videos

  • Short-term or past PHT use shows little risk increase.
  • Current, long-term PHT use is associated with a duration-dependent increase in breast cancer risk.

    • Conclusions:

    • The breast cancer risk associated with OCs appears to be small and transient.
    • The increased breast cancer risk from long-term PHT use warrants careful consideration against its benefits.