Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Melatonin

M J Cupp1

  • 1West Virginia University School of Pharmacy, Morgantown, USA.

American Family Physician
|October 24, 1997
PubMed
Summary

Melatonin, a hormone regulating sleep-wake cycles, shows potential for insomnia treatment. However, over-the-counter products lack guaranteed quality, and more research is needed on its safety and effectiveness.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Herbal remedies: adverse effects and drug interactions.

American family physician·1999
Same author

Glucosamine sulfate use in osteoarthritis.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·1999
Same author

Doxorubicin dosage guidelines in a patient with hyperbilirubinemia of Gilbert's syndrome.

The Annals of pharmacotherapy·1998
Same author

Kava: an herbal sedative.

The Nurse practitioner·1998
Same author

Use and abuse of flunitrazepam.

The Annals of pharmacotherapy·1998
Same author

Cytochrome P450: new nomenclature and clinical implications.

American family physician·1998

Area of Science:

  • Endocrinology
  • Sleep Medicine

Background:

  • Melatonin is a hormone synthesized by the pineal gland.
  • It plays a crucial role in regulating circadian rhythms and the sleep-wake cycle.

Purpose of the Study:

  • To evaluate the potential of melatonin as a therapeutic agent for insomnia.
  • To highlight the current limitations in understanding its safety and efficacy.

Main Methods:

  • Review of existing clinical studies and scientific literature on melatonin.
  • Analysis of the regulatory status and availability of melatonin supplements.

Main Results:

  • Melatonin demonstrates potential in managing sleep-wake cycle disturbances.
  • Significant variability exists in the potency, purity, and quality of commercially available melatonin products.
  • Limited large-scale clinical trial data is available regarding melatonin's efficacy and safety profile.

Conclusions:

  • Melatonin may become an accepted insomnia therapy pending further research.
  • Current over-the-counter melatonin products lack assured quality and safety.
  • Extensive clinical trials are necessary to address safety concerns, drug interactions, and effects on various health conditions before widespread acceptance.

Related Experiment Videos