[An epidemiological investigation for gram-positive coccus, especially MRSA, in Kinki area]

An epidemiological investigation for Methicillin-resistant Staphylococcus aureus (MRSA) was performed at 21 medical institutes in Kinki area by the questionnaire from Kinki Infection Working Group in 1995. The most frequent specimen for MRSA was pus (25.3%) from out-patients and sputum (34.4%) from in-patients, respectively. As compared to the investigation of the MRSA Forum in 1992 and 1993, MRSA increased over 20%, and furthermore 57.8% was MRSA out of S. aureus under this study. It demonstrated that drug-resistance was accelerated for a few years. Polymicrobial infection, especially with more than 3 pathogens, increased significantly compared with the results of the MRSA Forum (p < 0.01). It was suggested that compromized host increased and therapy turned to be more difficult. Simultaneous pathogens detected with MRSA were Candida species, Pseudomonas aeruginosa and Enterococcus faecalis. In terms of chemosusceptibility, VCM (99.9%), ST (99.4%) and ABK (99.3%) were still determined to be highly sensitivity against MRSA.