[Post-clinical period of disease: metabolic aspects]

Examining the biochemical processes in the rehabilitative period after diseases of vascular and inflammatory genesis showed it expedient to identify an asymptomatic postclinical period of disease as an independent stage of metabolic remission. The guideline for assessing the completeness of metabolic processes was to study such indices reflecting the nonspecific pathological and etiological essence of diseases as erythrocytic phospholipids and fatty acids, as well as indices of the lipid peroxidation-antioxidative defense system, a lysosomal enzyme beta-glucosidase, uric acid and hydroxyproline. The duration of an asymptomatic postclinical stage was found to be determined by the time of completeness of metabolic processes and to be 3-12 months after the onset of clinical recovery.