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Updated: Aug 19, 2026

Multiplex Detection of Bacteria in Complex Clinical and Environmental Samples using Oligonucleotide-coupled Fluorescent Microspheres
Published on: October 23, 2011
[Evaluation of the sensitivity and specificity of methods of rapid diagnosis in bacterial vaginosis]
Abstract:
Bacterial vaginosis was diagnosed in 35.8% of 109 patients of a reproductive age complaining of discharge from the genital tract. In 33% of cases bacterial vaginosis was associated with vaginal candidiasis. The most sensitive and specific method of rapid diagnosis of bacterial vaginosis is microscopic examination of Gram-stained smears, which may be used as a diagnostic method, whose sensitivity and specificity are almost 100%. Such tests as pH-metry, amine test, "key" cells, and assessment of vaginal discharge (normal or abnormal), should be used in complex. They may be performed by the therapist screening patients to detect bacterial vaginosis.
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