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A canine encephalomyelopathy with morphological abnormalities in mitochondria
O Brenner1, A de Lahunta, J F Cummings
1Department of Pathology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853-6140, USA.
Acta Neuropathologica
|October 28, 1997
Summary
A dog developed a progressive brain and spinal cord disease, showing ataxia and behavioral changes. Neuropathology revealed mitochondrial abnormalities and neuronal loss, similar to human mitochondrial encephalomyopathies.
Area of Science:
- Veterinary Neurology
- Neuroscience
- Mitochondrial Diseases
Background:
- Progressive encephalomyelopathies can affect young animals.
- Mitochondrial disorders are a group of debilitating human diseases.
- Canine neurological cases offer insights into comparative pathology.