Robust multivariate statistics and the prediction of protein secondary structure content

Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies.

European journal of medicinal chemistry·2025

Hazardous element inertisation in vitrified silicate ceramics: Effect of different matrices.

Journal of hazardous materials·2024

Development of an intervention to manage knee osteoarthritis risk and symptoms following anterior cruciate ligament injury.

Osteoarthritis and cartilage·2021

Fundamentals of osteoarthritis: outcome evaluation with patient-reported measures and functional tests.

Osteoarthritis and cartilage·2021

Immediate outcomes following the GLA:D® program in Denmark, Canada and Australia. A longitudinal analysis including 28,370 patients with symptomatic knee or hip osteoarthritis.

Osteoarthritis and cartilage·2021

Heating events in the nascent solar system recorded by rare earth element isotopic fractionation in refractory inclusions.

Science advances·2021

pH-responsive polymer-assisted refolding of urea- and organic solvent-denatured alpha-chymotrypsin.

Protein engineering·2004

Evaluation of different linker regions for multimerization and coupling chemistry for immobilization of a proteinaceous affinity ligand.

Protein engineering·2004

Recombinant porcine intestinal carboxylesterase: cloning from the pig liver esterase gene by site-directed mutagenesis, functional expression and characterization.

Protein engineering·2004

Periplasmic expression of human growth hormone via plasmid vectors containing the lambdaPL promoter: use of HPLC for product quantification.

Protein engineering·2004

Shift of fibril-forming ability of the designed alpha-helical coiled-coil peptides into the physiological pH region.

Protein engineering·2004

Modified peptide selection in vitro by introduction of a protein-RNA interaction.

Protein engineering·2004

Siteomix: a PyMOL plugin for the detection, alignment, and similarity analysis of protein‒ligand binding sites.

Journal of computer-aided molecular design·2026

Guardians of splicing: quality control mechanisms of snRNA variants.

Genes & development·2026

A high-throughput strategy for screening umami peptides from Chouguiyu based on peptidomics and machine learning-assisted molecular simulation.

Food research international (Ottawa, Ont.)·2026

PregBase: A comprehensive knowledge base for clinically relevant knowledge representation and biomarker prediction in pregnancy.

Artificial intelligence in medicine·2026

Machine Learning Prediction and Experimental Validation of Antimicrobial Peptide Activity Differences against Gram-Positive and Gram-Negative Bacteria.

ACS omega·2026

Comparative machine learning analysis identifies random forest and adaboost as superior models for the evaluation of semen quality and reproductive hormones.

Frontiers in reproductive health·2026

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Robust multivariate statistics and the prediction of protein secondary structure content

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Rational optimization of D3R/GSK-3β dual target-directed ligands as potential treatment for bipolar disorder: Design, synthesis, X-ray crystallography, molecular dynamics simulations, in vitro ADME, and in vivo pharmacokinetic studies.

Hazardous element inertisation in vitrified silicate ceramics: Effect of different matrices.

Development of an intervention to manage knee osteoarthritis risk and symptoms following anterior cruciate ligament injury.

Fundamentals of osteoarthritis: outcome evaluation with patient-reported measures and functional tests.

Immediate outcomes following the GLA:D® program in Denmark, Canada and Australia. A longitudinal analysis including 28,370 patients with symptomatic knee or hip osteoarthritis.

Heating events in the nascent solar system recorded by rare earth element isotopic fractionation in refractory inclusions.

pH-responsive polymer-assisted refolding of urea- and organic solvent-denatured alpha-chymotrypsin.

Evaluation of different linker regions for multimerization and coupling chemistry for immobilization of a proteinaceous affinity ligand.

Recombinant porcine intestinal carboxylesterase: cloning from the pig liver esterase gene by site-directed mutagenesis, functional expression and characterization.

Periplasmic expression of human growth hormone via plasmid vectors containing the lambdaPL promoter: use of HPLC for product quantification.

Shift of fibril-forming ability of the designed alpha-helical coiled-coil peptides into the physiological pH region.

Modified peptide selection in vitro by introduction of a protein-RNA interaction.

Siteomix: a PyMOL plugin for the detection, alignment, and similarity analysis of protein‒ligand binding sites.

Guardians of splicing: quality control mechanisms of snRNA variants.

A high-throughput strategy for screening umami peptides from Chouguiyu based on peptidomics and machine learning-assisted molecular simulation.

PregBase: A comprehensive knowledge base for clinically relevant knowledge representation and biomarker prediction in pregnancy.

Machine Learning Prediction and Experimental Validation of Antimicrobial Peptide Activity Differences against Gram-Positive and Gram-Negative Bacteria.

Comparative machine learning analysis identifies random forest and adaboost as superior models for the evaluation of semen quality and reproductive hormones.

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Robust multivariate statistics and the prediction of protein secondary structure content

Related Concept Videos

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