Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pseudohypertriglyceridaemia

R Valero1, C Atlan-Gepner, H Portugal

  • 1Service de Nutrition, Maladies Métaboliques et Endocrinologie, Hôpital Sainte Marguerite, CHU Marseille, France.

Diabetes & Metabolism
|October 29, 1997
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Retraction Note: Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii.

International journal of obesity (2005)·2024
Same author

Retraction Note: Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli.

International journal of obesity (2005)·2024
Same author

Use of the continuous glucose monitoring system to treat insulin autoimmune syndrome: quantification of glucose excursions and evaluation of treatment efficacy.

Diabetic medicine : a journal of the British Diabetic Association·2014
Same author

Mutation update and uncommon phenotypes in a French cohort of 96 patients with WFS1-related disorders.

Clinical genetics·2014
Same author

RETRACTED ARTICLE: Culturomics identified 11 new bacterial species from a single anorexia nervosa stool sample.

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology·2013
Same author

Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli.

International journal of obesity (2005)·2013
Same journal

Glucagon-like peptide-1 receptor agonists and risk of pancreaticobiliary cancers in patients with type 2 diabetes: a nationwide cohort study.

Diabetes & metabolism·2026
Same journal

Decreased risk of new-onset osteoporosis in patients with Type 2 diabetes on SGLT-2 inhibitors.

Diabetes & metabolism·2026
Same journal

Two faces of autoimmune hyperinsulinemia: contrasting type B insulin resistance syndrome and exogenous insulin antibody syndrome.

Diabetes & metabolism·2026
Same journal

CGM-based metrics and mortality in older adults living with type 2 diabetes on insulin therapy: a secondary analysis of the HYPOAGE study.

Diabetes & metabolism·2026
Same journal

Persistent burden and management gaps of hypoglycemia in pediatric type 1 diabetes: insights from the Epi-GLUREDIA Study.

Diabetes & metabolism·2026
Same journal

Blood oxygen saturation and its associations with autonomic and peripheral neuropathy in diabetes.

Diabetes & metabolism·2026
See all related articles

Pseudohypertriglyceridaemia can occur due to increased plasma glycerol from glycerol kinase deficit. This highlights the need for glycerol assays to accurately interpret triglyceride levels.

Area of Science:

  • Biochemistry
  • Clinical Diagnostics
  • Metabolic Disorders

Background:

  • Automated triglyceride assays are widely used for clinical diagnostics.
  • These assays may misinterpret elevated glycerol levels as hypertriglyceridemia.
  • Glycerol kinase deficit can lead to hyperglycerolemia, causing pseudohypertriglyceridemia.

Observation:

  • Two cases of pseudohypertriglyceridemia due to hyperglycerolemia were identified.
  • Clinical and biological features suggested the underlying glycerol kinase deficit.
  • Standard triglyceride assays lack a negative control for glycerol levels.

Findings:

  • Elevated plasma glycerol levels can mimic high triglyceride levels.
  • Glycerol kinase deficit is a rare cause of pseudohypertriglyceridemia.

Related Experiment Videos

  • The absence of a glycerol assay in standard triglyceride testing can lead to diagnostic errors.

    • Implications:

    • Accurate interpretation of plasma triglyceride levels requires consideration of potential hyperglycerolemia.
    • Implementing glycerol assays alongside triglyceride tests can prevent misdiagnosis.
    • Early diagnosis of glycerol kinase deficit is crucial for managing metabolic disorders.