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Analysis of trifluoroacetic acid in lyophilized natural products by capillary electrophoresis

M A Strege¹, W G Mascher

¹Lilly Research Laboratories, Eli Lilly and Co., Indianapolis, IN 46285, USA.

Journal of Chromatography. B, Biomedical Sciences and Applications

|October 29, 1997

Abstract:

A rapid and simple method for the capillary electrophoretic determination of residual trifluoroacetic acid in lyophilized natural products is described. The technique utilizes 2,6-naphthalenedicarboxylic acid as a separation buffer additive providing indirect ultraviolet absorption detection. Using this method, acceptable precision, accuracy, selectivity, range and linearity were achieved.

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