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QT interval changes following neck dissection. A stratified prospective study

C H Rassekh1, K C Dellsperger, J A Hokanson

  • 1Department of Otolaryngology, University of Texas Medical Branch, Galveston 77555-0521, USA.

The Annals of Otology, Rhinology, and Laryngology
|October 29, 1997
PubMed
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This study found no significant QT interval prolongation after neck dissection, contrasting European reports. While surgeons should remain aware, significant cardiac risks appear rare in this patient cohort.

Area of Science:

  • Cardiology
  • Otolaryngology
  • Surgical Oncology

Background:

  • European studies suggest neck dissection, particularly right radical neck dissection, may prolong the QT interval.
  • QT interval prolongation is a risk factor for sudden cardiac arrest.
  • Previous reports indicate potential cardiac complications following right radical neck dissection.

Purpose of the Study:

  • To investigate the prevalence of QT interval prolongation after various neck dissection procedures.
  • To compare preoperative and postoperative QT intervals in patients undergoing neck dissection.
  • To assess the impact of dissection type and side on QT interval changes.

Main Methods:

  • Retrospective analysis of electrocardiogram tracings from 45 patients.
  • Comparison of preoperative and postoperative corrected QT intervals.

Related Experiment Videos

  • Stratification of patients by neck dissection type (unilateral, bilateral, radical, modified, selective, carotid artery resection) and side (left, right, both).

    • Main Results:

    • No significant change in the corrected QT interval was observed between preoperative and postoperative measurements for all subjects.
    • Stratification by dissection type or side did not reveal significant QT interval differences.
    • No malignant arrhythmias were encountered during the study period.

    Conclusions:

    • Contrary to European findings, this study indicates no significant predictable QT interval prolongation after neck dissection.
    • Postoperative QT interval prolongation following neck dissection appears to be a rare occurrence in the absence of other risk factors.
    • Head and neck surgeons should maintain awareness of potential, albeit rare, cardiac risks.