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Updated: Jul 22, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
Painful knee joint prostheses: evaluation for loosening by combined radionuclide arthrography and transmission
Unlabelled:
Interpretation of radionuclide arthrograms (RNA) of the knee after total knee joint replacement (TKR) may be difficult because of the lack of sufficient anatomic reference information. Additional transmission images may provide the necessary reference information required for correct interpretation of RNA of the knee.
Methods:
Tc-99m tin colloid (20 MBq) RNA was combined with cobalt-57 transmission imaging in six patients with painful TKRs in whom loosening of the TKR was suspected. Knee surgery was then performed on these six cases.
Results:
RNA correctly detected loosening of the tibial component in five of six cases, but did not detect loosening of the femoral component in any of three cases.
Conclusion:
RNA combined with transmission imaging is recommended for detection of loosening of the tibial component of a TKR. RNA may not be of value for detecting loosening of the femoral component.
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