Carcinoma cervicis uteri. Treatment results from the period 1953--1968

During the course of 16 years, i. e. from 1953 to 1968 inclusively, a total of 2111 patients with carcinoma of the uterine cervix were treated at the Oncological Institute in Brno. Of these, 1829 patients, i. e. 86.6% were irradiated, 282, i. e. 13.4% underwent primarily a radical excision and subsequently were irradiated. During the past years, approximately 95% of all such patients are being given radical irradiation. The mean age is 52.7 years, the sixth decade being numerically the highest in incidence -- 27.4%. The distribution pattern according to the tumor stage: I -- 29.3%, II -- 14.3%, III -- 48.2%, IV -- 8.2%. This distribution remained practically unchanged over the follow-up period of 16 years. The fundamental method treatment of practically 87% of all the patients was actinotherapy consisting in a combined application of radium and X-rays. Of the total number of 2111 patients, 1298, i. e. 61.5% have survived 5 years without any symptoms of the disease, 966 patients, i. e. 59.0% (out of a total of 1671 patients) survived 10 years. The five-year survival symptom-free period for the various stages ia as follows: I -- 82.5%, II -- 77.1%, III -- 52.8% and IV -- 9.8%. A comparison of the results of treatment in patients radically irradiated and those primarily operated upon then subsequently irradiated, i. e. in 619 patients of stage I showed the 5-year recovery to be superior by almost 4% in the former than in the latter group --84.1% as against 80.3%. Over the last 6 years of the follow-up, i. e. 1962--1968, this difference went up to 6.0% in favour of those radically irradiated--85.1% as against 79.2%. An increasing mortality rate due to carcinoma is noted with advancing age.