[Current resistence situation in a surgical and urological department]

Area of Science:

• Medical Microbiology
• Clinical Bacteriology

Background:

• Bacterial infections in surgical and urological settings pose significant clinical challenges.
• Understanding the evolving spectrum and antibiotic sensitivity of pathogens is crucial for effective treatment.

Purpose of the Study:

• To investigate the spectrum of bacterial isolates from wound smears and urine specimens.
• To determine the antibiotic sensitivity patterns of these bacteria over time.
• To evaluate the emergence of antibiotic resistance in clinical settings.

Main Methods:

• Analysis of 534 positive wound smears and 7879 urine specimens.
• Bacterial identification and antibiotic sensitivity testing using 9 current antibiotics and chemotherapeutics.
• Data collected from Surgical and Urological Clinics between 1969-1971 and in 1973.

Main Results:

• Escherichia coli was the most common organism in both wound and urine samples.
• Other prevalent bacteria included Staphylococcus aureus, Aerobacter, Proteus, Enterococci, and Pseudomonas.
• No significant increase in bacterial resistance to tested antibiotics, including Ampicillin, was observed during the study period.
• A decrease in Enterococci and an increase in E. coli, Proteus, and Pseudomonas were noted.

Conclusions:

• The study supports the continued use of bactericidal antibiotics, particularly from the penicillin group, for specific clinical indications.
• Stable antibiotic sensitivity patterns suggest current therapeutic strategies remain effective against common pathogens.
• Ongoing surveillance of bacterial spectrum and resistance is essential for antimicrobial stewardship.