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Removal of intracanal smear by doxycycline in vitro
R A Barkhordar1, L G Watanabe, G W Marshall
1Department of Restorative Dentistry, School of Dentistry, University of California, San Francisco, USA.
Unlabelled:
Cleansing and shaping result in a smear layer on the instrumented canal wall surfaces. The smear layer may inhibit close contact between sealers and dentin, and inhibits diffusion of medicaments.
Objective:
This study assessed the effect of doxycycline hydrochloride (DH) on smear layer on intracanal walls.
Study Design:
Scanning electron microscopy was used to evaluate the remaining smear layer using different concentrations of DH. Single-canal palatal roots of extracted maxillary molars were irrigated with saline-15% EDTA; saline-25 mg/ml DH; saline-50 mg/ml DH; saline-100 mg/ml DH; NaOCl-15% EDTA; NaOCl-25 mg/ml DH; NaOCl-50 mg/ml DH; and NaOCl-100 mg/ml DH. The roots were fractured into halves and the amount of smear layer assessed in the middle and apical third.
Results:
Doxycycline-HCl of 100 mg/ml was the most effective in removing smear layer. In the saline group, 100 mg/ml of DH was more effective than EDTA. In the hypochlorite group, 50 mg/ml and 100 mg/ml of DH were more effective than EDTA (p < 0.05).
Conclusion:
Doxycycline solution may be an effective irrigant.
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