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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Acute pancreatitis secondary to ifosfamide
R Gerson1, A Serrano, A Villalobos
1Unidad de Quimioterapia, Hospital General de Mexico, Mexico City, Mexico.
Acute pancreatitis can occur in cancer patients due to the malignancy or its treatment. This case highlights a rare instance of acute pancreatitis developing after ifosfamide administration in a patient with lung cancer.
Area of Science:
- Oncology
- Gastroenterology
- Pharmacology
Background:
- Acute pancreatitis is a known complication in cancer patients.
- It can arise from the malignancy itself or as a side effect of cancer therapies.
- Antineoplastic agents, while effective, can present unique toxicities.
Observation:
- A 65-year-old woman with small cell lung cancer was treated with ifosfamide.
- The patient had no pancreatic metastases from her cancer.
Findings:
- The patient developed acute pancreatitis following ifosfamide administration.
- This represents a rare adverse event associated with ifosfamide treatment.
Implications:
- Clinicians should consider ifosfamide-induced pancreatitis in cancer patients presenting with acute pancreatitis.
- Further investigation may be warranted to understand the mechanism of ifosfamide-induced pancreatitis.
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