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Physiologic and structural changes associated with aging skin
1Department of Dermatology, University of California, San Francisco, USA.
Dermatologic Clinics
|December 31, 1997
Summary
Photoaging in human skin progresses visibly, causing anatomical and structural changes. Evaluating these changes macroscopically and microscopically helps physicians choose treatments for sun damage.
Area of Science:
- Dermatology
- Aging Research
- Photobiology
Background:
- Photoaging encompasses a spectrum of skin changes due to chronic sun exposure.
- These changes range from subtle to profound, affecting skin anatomy and structure.
- Understanding these alterations is crucial for effective treatment selection.
Purpose of the Study:
- To outline the progression of photoaging in human skin.
- To discuss methods for qualifying and quantifying photoaging changes.
- To highlight the importance of matching therapeutic approaches to specific solar damage problems.
Main Methods:
- Observational analysis of photoaging spectrum.
- Macroscopic and microscopic evaluation of skin changes.
- Review of therapeutic approaches for chronic solar damage.
Main Results:
- Photoaging presents a recognizable progression of skin changes.
- Macroscopic and microscopic assessments aid in understanding the severity of damage.
- Current therapeutic strategies can be evaluated based on these assessments.
Conclusions:
- The spectrum of photoaging is well-defined, with progressive changes.
- Objective qualification and quantification of skin aging are essential.
- Further comparative studies are needed to optimize treatment selection for photoaging.