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Zeis gland carcinoma
1Department of Dermatology, National Sapporo Hospital, Japan.
The Journal of Dermatology
|November 14, 1997
Summary
This report details a rare case of sebaceous carcinoma of the Zeis gland in a 90-year-old man. Surgical removal was successful, with no recurrence noted during follow-up.
Area of Science:
- Ophthalmology
- Dermatopathology
- Oncology
Background:
- Sebaceous carcinoma of the Zeis gland is an uncommon malignant eyelid tumor.
- This specific type of carcinoma arises from the sebaceous glands associated with eyelash follicles.
Observation:
- A 90-year-old Japanese male presented with a 12 x 3-mm, papillomatous nodule on the left upper eyelid.
- The lesion was reddish with partial yellowing and associated with eyelash loss.
Findings:
- Histological examination revealed two distinct cell types: dark basaloid and larger pale cells.
- The tumor exhibited lobular and comedo-acinar growth patterns.
Implications:
- This case contributes to the limited literature on Zeis gland sebaceous carcinoma.
- Early diagnosis and surgical excision are crucial for managing this rare eyelid malignancy.