[Adenopathies and anticonvulsants: Lymphoma or drug reaction?]

In this paper the authors present the clinical case of a nine years old girl with adenopathy, fever and important weight loss. 10 months after she begins with diphenidantoin the differential diagnosis was attempted between lymphoma and drug reaction. The authors reviewed the literature pointed out the development of lymphomas in patients on diphenidantoin therapy. They mention the different hipothesis to explain this drug-lymphoma interrelation concluding that there is necessary more studies and experience in future cases to clarify the certain role of the anticonvulsivants in the production of this abnormalities.