[The rate of cortisol secretion in thyrotoxicosis patients]

The rate of cortizol secretion was determined in 5 healthy persons and 18 patients suffering from thyrotoxicosis by dilution of isotopic label by the mean specific radioactivity of tetrahydrocortizol and tetrahydrocortisone excreted with the urine. There was revealed a close direct dependence of the adrenal gland activation on decompensation of the disease and a reverse dependence on the duration of thyrotoxicosis. The rate of cortizol secretion had a tendency to reduction and normalization in medicinal compensation of thyrotoxicosis.