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Homocysteine: a new risk factor for atherosclerosis
P C Fallest-Strobl1, D D Koch, J H Stein
1University of Wisconsin-Madison Medical School, USA.
American Family Physician
|November 14, 1997
Summary
High homocysteine levels are a significant risk factor for atherosclerosis and related vascular events. Lowering homocysteine with folic acid supplements is a safe and effective treatment for hyperhomocysteinemia.
Area of Science:
- Cardiovascular Science
- Metabolic Disorders
- Vascular Biology
Background:
- Accumulating evidence links elevated homocysteine to atherosclerosis.
- High plasma homocysteine concentration contributes to arterial wall pathology.
- This elevation is associated with increased risk of cardiovascular, cerebrovascular, and peripheral vascular events.