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Who should receive recombinant factor VIII?
1Oxford Haemophilia Centre, Churchill Hospital, UK.
Recent guidelines published by the United Kingdom Haemophilia Centre Directors' Organisation state that recombinant factor VIII constitutes the treatment of choice for all patients with haemophilia A. However, certain categories may have to be accorded priority as financial resources are limited. The general order of priority for the introduction of recombinant factor VIII is (1) previously untreated patients, (2) human immunodeficiency virus (HIV)- and hepatitis C-negative patients, (3) HIV-negative, hepatitis C-positive patients and (4) patients seropositive for anti-HIV.
Recent guidelines published by the United Kingdom Haemophilia Centre Directors' Organisation state that recombinant factor VIII constitutes the treatment of choice for all patients with haemophilia A. However, certain categories may have to be accorded priority as financial resources are limited. The general order of priority for the introduction of recombinant factor VIII is (1) previously untreated patients, (2) human immunodeficiency virus (HIV)- and hepatitis C-negative patients, (3) HIV-negative, hepatitis C-positive patients and (4) patients seropositive for anti-HIV.