Solitary lytic lesion of the skull

Thyroid carcinoma metastatic to the calvaria may result in a lytic, well-circumscribed lesion the appearance of which necessitates differential consideration of lytic lesions of the skull. The merits of angiography in the study of such lesions are noted. Even in young persons, the possibility of metastasis presenting as a solitary lytic defect in the skull must be kept in mind.