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Methodological issues in the use of biological markers in cancer epidemiology: cohort studies
1Harvard School of Public Health, Department of Epidemiology, Boston, MA 02115, USA.
IARC Scientific Publications
|January 1, 1997
Abstract:
In this chapter we summarize the major strengths and weaknesses of cohort studies; consider how these characteristics influence the use of biomarkers in cohort studies; briefly review considerations of statistical power, design and the influence of measurement error in cohort studies; and discuss some of the emerging ethical considerations that relate to the use of biomarkers in prospective studies.