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Cognitive impairment in adolescents with schizophrenia
J T Kenny1, L Friedman, R L Findling
1Department of Psychiatry, Case Western Reserve University School of Medicine, Cleveland, Ohio 44141, USA.
Objective:
The purpose of this study was to determine whether adolescent schizophrenia is characterized by neuropsychological deficits.
Method:
The performance on a battery of neuropsychological tests of 17 adolescents with schizophrenia (mean age = 15.71 years) was compared with that of 17 normal adolescents (mean age = 15.12 years).
Results:
Compared with the normal subjects, the patients were impaired on 10 of the 13 measures; larger effect sizes were shown for measures involving working memory and attention than for those involving secondary memory, generative naming, and executive functions.
Conclusions:
Adolescents with schizophrenia have generalized cognitive dysfunction, which is most apparent on tests of attention and working memory.