Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Digital tomosynthesis in breast imaging

L T Niklason1, B T Christian, L E Niklason

  • 1Department of Radiological Sciences, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

Radiology
|November 14, 1997
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The impact of cardiorespiratory fitness on Alzheimer's disease biomarkers and their relationships with cognitive decline.

medRxiv : the preprint server for health sciences·2025
Same author

Cardiorespiratory Fitness Modifies the Relationship Between Arterial Stiffness and Cerebral Blood Flow Independent of Physical Activity.

medRxiv : the preprint server for health sciences·2025
Same author

[Characteristics and additive effect of hearing loss induced by diabetes mellitus and noise].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2022
Same author

Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline.

Alzheimer's & dementia (New York, N. Y.)·2020
Same author

[Esculin inhibits proliferation of triple negative breast cancer cells by down-regulating FBI-1].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2020
Same author

[Comparison of modeling effects of two different 7, 12-dimethylbenz[a] anthracene induced breast cancer models in tree shrew].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2019
Same journal

Noncontrast Abbreviated MRI for Post-TACE Treatment Response Monitoring of Hepatocellular Carcinoma Based on Ancillary Features from LI-RADS.

Radiology·2026
Same journal

Response Evaluation Criteria in Bone Metastases: Performance and Association of Response Classifications with Survival Outcomes.

Radiology·2026
Same journal

Entropy for Prediction of MACEs in Myocarditis: A Cardiac MRI-based Biomarker of Myocardial Tissue Heterogeneity.

Radiology·2026
Same journal

AI for Radiology: A Primer Part II. Interacting with AI Results.

Radiology·2026
Same journal

Hyperdense Capsule Sign at Noncontrast CT as an Indication for Middle Meningeal Artery Embolization for Nonacute Subdural Hematomas: A MAGIC-MT Trial Post Hoc Analysis.

Radiology·2026
Same journal

Sawtooth Cardiomyopathy: The Tiger Heart.

Radiology·2026
See all related articles
This summary is machine-generated.

This study introduces a tomosynthesis breast imaging method using digital mammography systems. Tomosynthesis shows improved lesion visibility and may enhance early breast cancer detection, particularly in dense breasts.

Area of Science:

  • Radiology
  • Medical Imaging
  • Oncology

Background:

  • Digital mammography is a standard for breast cancer screening.
  • Improving the accuracy and early detection capabilities of mammography remains a key goal.

Purpose of the Study:

  • To describe and evaluate a novel tomosynthesis breast imaging technique.
  • Assess the efficacy of tomosynthesis compared to conventional mammography.

Main Methods:

  • Acquired low-dose tomosynthesis images using a moving x-ray source and stationary detector.
  • Utilized a step-and-expose imaging protocol.
  • Evaluated images of phantoms and mastectomy specimens with experienced readers.

Main Results:

  • Tomosynthesis enables full breast tomographic imaging from a single x-ray source arc.

Related Experiment Videos

  • Radiation dose is comparable to single-view mammography.
  • Tomosynthesis images generally surpassed conventional mammography in lesion visibility and margin definition.

    • Conclusions:

    • Digital mammographic systems can facilitate breast tomosynthesis.
    • Tomosynthesis offers potential improvements in mammographic specificity and early cancer detection.
    • This technique may be particularly beneficial for women with dense breasts.