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Related Experiment Videos

Pattern of solid malignant tumours in children--a ten-year study

R Pramanik1, C C Paral, A Ghosh

  • 1Department of Pathology, NRS Medical College, Calcutta.

Journal of the Indian Medical Association
|April 1, 1997
PubMed
Summary

This study analyzed 263 pediatric solid tumors, finding retinoblastoma most common. Pediatric cancer incidence varied by age, with a male predominance observed in children under 14.

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Area of Science:

  • Pediatric Oncology
  • Cancer Epidemiology
  • Tumor Pathology

Background:

  • Solid malignant tumors in children represent a significant health challenge.
  • Understanding the epidemiological patterns of these tumors is crucial for diagnosis and treatment.
  • Previous studies have highlighted variations in tumor types and incidence based on age and sex.

Purpose of the Study:

  • To characterize the spectrum and incidence of solid malignant tumors in children up to 14 years of age.
  • To identify age-specific and sex-specific patterns in pediatric solid tumors.
  • To provide epidemiological data for retinoblastoma, Wilms' tumor, lymphoma, and other embryonal tumors.

Main Methods:

  • Retrospective analysis of 263 solid malignant tumors (excluding CNS tumors) in children up to 14 years.
  • Tumor classification based on histopathology.
  • Data collection on patient age, sex, and tumor type.
  • Epidemiological analysis of incidence and distribution.

Main Results:

  • Retinoblastoma (27%) was the most frequent tumor, followed by Wilms' tumor (14.1%) and lymphoma (13.7%).
  • The majority of patients (55%) were under 5 years old, with a higher incidence of embryonal tumors in this age group.
  • A male preponderance was observed (1.6:1 male to female ratio).
  • Notable tumors included Ewing's sarcoma (n=21), osteogenic sarcoma (n=19), and germ cell tumors (n=14).

Conclusions:

  • Pediatric solid tumors exhibit distinct epidemiological profiles based on age and sex.
  • Retinoblastoma is the leading solid tumor in this pediatric cohort.
  • Further research into specific tumor types like embryonal rhabdomyosarcoma and neuroblastoma is warranted.

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