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Published on: July 1, 2018
Primary meningococcal arthritis: case report and review of the literature
1Department of Medicine, Saint Joseph Hospital, Denver, CO 80218, USA.
Abstract:
Meningococcal arthritis is a recognized manifestation of Neisseria meningitidis infection, the presentation of which may be confusing. Although arthritis occurs in the setting of meningococcal meningitis, it may also be seen as a primary event without neurological involvement and with or without cutaneous manifestations. We describe a patient with primary meningococcal arthritis and review the literature relating to the clinical types and pathogenic mechanisms. Comparisons of patient series from 1980 to the present with those reported before 1980 are described.
Insights
Meningococcal arthritis, a complication of Neisseria meningitidis, can occur independently of meningitis. This review examines its varied clinical presentations and pathogenesis, comparing recent cases with historical data.
Area of Science:
- Rheumatology
- Infectious Diseases
- Microbiology
Background:
- Meningococcal arthritis is a known complication of Neisseria meningitidis infection.
- Its clinical presentation can be variable and sometimes confusing.
- It may occur with or without meningitis and skin manifestations.
Observation:
- This study describes a case of primary meningococcal arthritis.
- The literature on clinical types and pathogenic mechanisms was reviewed.
- Patient series from 1980 to the present were compared with earlier reports.
Findings:
- Neisseria meningitidis can cause arthritis as a primary event, separate from meningitis.
- The condition presents with diverse clinical features, including potential skin involvement.
- Analysis reveals shifts in presentation and understanding over time.
Implications:
- Recognizing primary meningococcal arthritis is crucial for timely diagnosis and treatment.
- Understanding the varied presentations aids in differentiating it from other causes of arthritis.
- This review provides updated insights into the pathogenesis and clinical spectrum of meningococcal arthritis.
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