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Pancreatitis in systemic scleroderma

N Sartori1, M Löhr, B Basan

  • 1Department of Medicine, University of Rostock, Germany.

Zeitschrift Fur Gastroenterologie
|November 14, 1997
PubMed
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This case study highlights a woman with recurrent pancreatitis linked to systemic lupus erythematosus. The findings emphasize the importance of considering autoimmune diseases in pancreatitis diagnosis.

Area of Science:

  • Internal Medicine
  • Gastroenterology
  • Rheumatology

Background:

  • Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse clinical manifestations.
  • Acute pancreatitis is a serious condition characterized by inflammation of the pancreas.
  • The association between SLE and acute pancreatitis is infrequently reported but clinically significant.

Observation:

  • A 61-year-old woman presented with symptoms of acute pancreatitis, including abdominal pain, nausea, vomiting, and fever.
  • Her medical history included acute rheumatism, pyelonephritis, and systemic scleroderma, with recurrent episodes of abdominal pain and elevated pancreatic enzymes since 1971.
  • Clinical examination revealed signs consistent with acute pancreatitis upon admission.

Findings:

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  • The patient's presentation suggests a potential link between her history of autoimmune conditions and the development of acute pancreatitis.
  • Elevated serum amylase and lipase levels were noted during recurrent episodes of abdominal pain.
  • The case prompts a review of the literature connecting systemic lupus erythematosus and acute pancreatitis.

    • Implications:

    • This case underscores the necessity of considering autoimmune diseases, particularly systemic lupus erythematosus, in the differential diagnosis of acute pancreatitis.
    • Further research into the pathogenic mechanisms linking SLE and pancreatitis may improve patient outcomes.
    • Early recognition and management of pancreatitis in SLE patients can potentially prevent severe complications.