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Related Experiment Videos

Be aware of abdominal tuberculosis

B J Bouma1, K M Tytgat, H G Schipper

  • 1Department of Internal Medicine, Academic Medical Centre, Amsterdam, Netherlands.

The Netherlands Journal of Medicine
|November 14, 1997
PubMed
Summary

Abdominal tuberculosis, often diagnosed late due to vague symptoms, requires prompt identification. Early diagnosis and treatment of intestinal tuberculosis and tuberculous peritonitis are crucial for patient outcomes.

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Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Microbiology

Background:

  • Abdominal tuberculosis (ATB) diagnosis is frequently delayed because symptoms like fever, abdominal pain, and weight loss are non-specific.
  • Patients from regions where tuberculosis is endemic are at higher risk for ATB.

Observation:

  • Two patients presented with prolonged fever, abdominal pain, and weight loss, indicative of potential ATB.
  • Diagnostic procedures, including colonoscopy and laparoscopy, were performed to obtain specimens.

Findings:

  • Acid-fast bacilli were identified in aspirate and biopsy samples.
  • Polymerase Chain Reaction (PCR) confirmed the presence of the Mycobacterium tuberculosis complex.
  • Mycobacterium tuberculosis was successfully cultured, confirming the diagnosis.

Implications:

  • Prompt diagnosis and initiation of antituberculous therapy led to positive patient responses.
  • Co-infection with Human Immunodeficiency Virus (HIV), or Acquired Immunodeficiency Syndrome (AIDS), was identified in one patient, highlighting the importance of screening.
  • This case series underscores the need for heightened clinical suspicion for ATB in endemic populations presenting with non-specific abdominal symptoms.

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