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Contribution of immunological mechanism in a case of ochronotic arthropathy
G Aliberti1, I Pulignano, M Proietta
1II Medical Clinic, University of Rome, La Sapienza, Italy.
Panminerva Medica
|November 14, 1997
Abstract:
We have studied cell mediated and humoral response on the synovial fluid and peripheral blood of a 60-year-old man affected by ochronosis. Results showed raised percentages of CD3+, CD8+, HLA-DR+ and CD25+ T cells, presence of TNF, enhanced levels of immunoglobulins and low levels of C3 in the synovial fluid, and a higher rate of HLA-DR+ and CD25+ T lymphocytes in peripheral blood. These data suggest a possible role of immunological response the evolution of an ochronotic arthropathy.