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Updated: Aug 12, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Emergency identification and treatment of acute ischemic stroke
1Department of Neurology, University of Texas Health Science Center, Houston, USA. kasner@mail.med.upenn.edu
Abstract:
In this review we describe the pathophysiology of cerebral ischemia and its implications for potential therapy. We summarize the results of recently completed trials of acute stroke intervention and explore some of the controversy surrounding thrombolysis for acute stroke. We also introduce the key concepts of neuroprotection and its therapeutic possibilities. Finally, we discuss the delays that may occur in the emergency evaluation and management of acute ischemic stroke and suggest some methods to expedite the process.
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