Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Progestins and bone

¹Department of Endocrinology, Academisch Ziekenhuis Utrecht, The Netherlands. j.thijssen@LAB.AZU.NL

Zentralblatt Fur Gynakologie

|January 1, 1997

Summary

This summary is machine-generated.

Progestins do not negatively impact estrogen's bone benefits in hormone replacement therapy. Instead, progestins may offer additional bone-sparing effects by stimulating bone formation.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

An in vivo ultrasonic model of liver parenchyma.

IEEE transactions on ultrasonics, ferroelectrics, and frequency control·2008

Same author

[Comparison of letrozole and exemestane used in non-adjuvant therapy of endometrial carcinoma].

Voprosy onkologii·2005

Same author

Importance of local aromatase activity in hormone-dependent breast cancer: a review.

Breast (Edinburgh, Scotland)·2004

Same author

Levels of estrogen and progesterone receptors in the myometrium and leiomyoma tissue after suppression of estrogens with gonadotropin releasing hormone analogs.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2002

Same author

Effects of progestins on bone: an update.

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology·2002

Same author

No evidence for participation of non-adrenergic non-cholinergic subtances in brain death-related hemodynamic deterioration of the feline potential heart donor.

Annals of transplantation·2002

Same journal

About 150 births naturally after previous Caesarean section.

Zentralblatt fur Gynakologie·2010

Same journal

About lutein cysts found in hydrops foetus et placentae.

Zentralblatt fur Gynakologie·2010

Same journal

The potencies of the burner epithelium, especially a tendency to form serous epitrel, squamous and mucosal epithelium.

Zentralblatt fur Gynakologie·2010

Same journal

Two double birth defects causing obstetric difficulties.

Zentralblatt fur Gynakologie·2010

Same journal

The uterine size and fundus level in the first part of pregnancy.

Zentralblatt fur Gynakologie·2010

Same journal

The crossbar interposition.

Zentralblatt fur Gynakologie·2010

See all related articles

Area of Science:

Endocrinology
Bone Biology
Pharmacology

Background:

Hormone replacement therapy (HRT) combines oestrogens with progestins.
The impact of progestins on oestrogen's bone-protective effects is a key area of research.

Purpose of the Study:

To review existing data on the effects of progestins and oestrogen/progestin combinations on bone health in women.
To assess whether progestins modulate the beneficial effects of oestrogens on bone.

Main Methods:

Literature review of studies examining progestin and oestrogen/progestin effects on bone.
Synthesis of data concerning bone density, bone turnover markers, and fracture risk.

Main Results:

No evidence suggests progestins negate the positive effects of oestrogens on bone.

Related Experiment Videos

Progestins demonstrate potential bone-sparing properties.

Evidence indicates progestins may stimulate bone formation, though mechanisms require further investigation.

Conclusions:

Progestins do not interfere with the bone benefits of oestrogen therapy.
Progestins may possess intrinsic bone-anabolic properties.
Further research is needed to elucidate the precise mechanisms of progestin-induced bone formation.