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Antimycobacterial activity of some 2,3-dianilinoquinoxaline derivatives
K Waisser1, R Beckert, M Slosáfrek
1Department of Inorganic Chemistry, Faculty of Pharmacy, Charles University, Hradec Králové, Czech Republic.
Die Pharmazie
|November 15, 1997
Abstract:
The antimycobacterial activity of 2,3-dianilinoquinoxaline derivatives was studied and the substances were found to be mostly wide-spectrum antimycobacterial agents. Replacement of one nitrogen atom in the heterocycle for oxygen or sulfur was usually accompanied by loss of activity. The model structure for the study was the wide-spectrum antimycobacterial drug clofazimine.